
Education
University of Notre Dame, 1979, BS, Microbiology; University of Michigan, 1981, MS, Microbiology and Immunology and 1984, PhD, Microbiology and Immunology
Professional Area
Dr. Shapiro’s research focuses on contributions of the transmembrane peptidase CD13 (aminopeptidase N) to cell function and pathologic processes. CD13 is a surprisingly multifunctional molecule that regulates diverse processes such as angiogenesis, inflammatory trafficking, antigen presentation, cell-matrix/cell-cell adhesion, coronavirus infection, maintenance of the stem cell niche and bone remodeling.
Citation
For significant contributions to the understanding of the regulations and function of cell surface peptidases in the angiogenic endothelium of tumors, vessels at sites of inflammation and in cardiovascular disease; her considerable breadth of expertise in a range of disciplines illustrates flexibility to explore new opportunities in diverse fields.